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Brugada Syndrome: Difference between revisions
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[[Image:brugada.jpg|thumb|right|Dr. Pedro Brugada. Pedro and Josep Brugada described in 1992 a landmark publication with a case-series of 8 patients with sudden cardiac death. <cite>Brugada</cite> Currently, three brothers of the Brugada family (Pedro, Josep and Ramon Brugada) conduct research in the syndrome that has been named after them.]] | [[Image:brugada.jpg|thumb|right|Dr. Pedro Brugada. Pedro and Josep Brugada described in 1992 a landmark publication with a case-series of 8 patients with sudden cardiac death. <cite>Brugada</cite> Currently, three brothers of the Brugada family (Pedro, Josep and Ramon Brugada) conduct research in the syndrome that has been named after them.]] | ||
[[Image:scn5a.jpg|thumb|right|The SCN5a gen is located on the short arm (p) of chromosome 3]] | [[Image:scn5a.jpg|thumb|right|The SCN5a gen is located on the short arm (p) of chromosome 3]] | ||
''Auteur: Louise R.A. Olde Nordkamp'' | |||
''Supervisor: Arthur A.M. Wilde'' | |||
'''Brugada syndrome''' refers to a hereditary disease that is associated with a risk of sudden cardiac death. It is characterized by typical ECG abnormalities: ST segment elevation in the precordial leads (V1 - V3). | '''Brugada syndrome''' refers to a hereditary disease that is associated with a risk of sudden cardiac death. It is characterized by typical ECG abnormalities: ST segment elevation in the precordial leads (V1 - V3). | ||
The Brugada brothers were the first to describe the characteristic ECG findings and link them to sudden death. Before that, the characteristic ECG findings, were often mistaken for a right ventricle myocardial infarction and already in 1953, a publication mentions that the ECG findings were not associated with ischemia as people often expected. | The Brugada brothers were the first to describe the characteristic ECG findings and link them to sudden death. Before that, the characteristic ECG findings, were often mistaken for a right ventricle myocardial infarction and already in 1953, a publication mentions that the ECG findings were not associated with ischemia as people often expected.<cite>osher</cite> | ||
==General features== | ==General features== | ||