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Brugada Syndrome: Difference between revisions
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'''"Lifestyle modification":''' | '''"Lifestyle modification":''' | ||
*All Brugada syndrome patients should avoid drugs that could manifest a type 1 ECG and VF. These drugs are listed on [http://www.brugadadrugs.org www.BrugadaDrugs.org] | *All Brugada syndrome patients should avoid drugs that could manifest a type 1 ECG and VF. These drugs are listed on [http://www.brugadadrugs.org www.BrugadaDrugs.org]. | ||
*Fever may also provoke type 1 ECG and VF. Patients with fever are advised to go to the hospital to make an ECG. When ECG changes are present, monitoring is warranted and antipyretics are needed. | *Fever may also provoke type 1 ECG and VF. Patients with fever are advised to go to the hospital to make an ECG. When ECG changes are present, monitoring is warranted and antipyretics are needed. | ||
'''Medication/Other therapies:''' | '''Medication/Other therapies:''' | ||
*[http://www.textbookofcardiology.org/index.php?title=W:nl:Internal_Cardiac_Defibrillator&action=edit&redlink=1 ICD | *[http://www.textbookofcardiology.org/index.php?title=W:nl:Internal_Cardiac_Defibrillator&action=edit&redlink=1 ICD] implantation is first line therapy in Brugada patients with a previous cardiac arrest, [http://www.textbookofcardiology.org/index.php?title=Ventricular_Tachycardia&action=edit&redlink=1 ventricular] tachycardia or cardiac [http://www.textbookofcardiology.org/wiki/Syncope syncope]. ICD implantation in asymptomatic patients is not advised and needs careful judgement regarding the low annual rate of arrhythmic events and high incidence rate of complications (7.5 per 100 patient-years). | ||
*In Brugada patients with recurrent VF events or ICD shocks, isoproterenol or quinidine are known to be effective for VF suppression in both children and adults. | *In Brugada patients with recurrent VF events or ICD shocks, isoproterenol or quinidine are known to be effective for VF suppression in both children and adults. | ||
*Ablation of a fractionated electrogram in the epicardial right ventricular outflow tract is a promising option for VF suppression in Brugada patients in a small study, but still has to be proven in larger cohorts of Brugada patients. | *Ablation of a fractionated electrogram in the epicardial right ventricular outflow tract is a promising option for VF suppression in Brugada patients in a small study, but still has to be proven in larger cohorts of Brugada patients. | ||