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The most important cause (65-70% of the cases) of HF in the Western world is ischaemic heart disease including myocardial infarction (vd wall). These patients mainly suffer systolic HF due to wall motion abnormalities of the affected and remodeling of the non-affected parts of the myocardium. | The most important cause (65-70% of the cases) of HF in the Western world is ischaemic heart disease including myocardial infarction (vd wall). These patients mainly suffer systolic HF due to wall motion abnormalities of the affected and remodeling of the non-affected parts of the myocardium. | ||
==== Hypertension | ==== Hypertension ==== | ||
In patients with a high blood pressure (BP), the heart faces an increased afterload (a higher workload pumping the blood against the increased vascular resistance). At longer duration, this will lead to hypertrophy of the cardiac myocardium. This thicker, stiffer myocardium has a decreased pump function compared with non-hypertrophic myocardium. Moreover, (chronic) hypertension is a risk factor for (coronary) atherosclerosis and thereby increases the risk of myocardial infarction and subsequent HF. In as much as 60-70% of patients suffering HF, hypertension is the primary or secondary cause. (vd wall) | In patients with a high blood pressure (BP), the heart faces an increased afterload (a higher workload pumping the blood against the increased vascular resistance). At longer duration, this will lead to hypertrophy of the cardiac myocardium. This thicker, stiffer myocardium has a decreased pump function compared with non-hypertrophic myocardium. Moreover, (chronic) hypertension is a risk factor for (coronary) atherosclerosis and thereby increases the risk of myocardial infarction and subsequent HF. In as much as 60-70% of patients suffering HF, hypertension is the primary or secondary cause. (vd wall) | ||
==== Heart rhythm disorders ==== | ==== Heart rhythm disorders ==== |
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