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Since the 20th century, cardiovascular diseases (CVD’s) have grown to be the leading cause of death and disability in the world, illustrated by 17.3 million deaths per year in 2008. Out of all cardiovascular diseases, coronary heart disease (46% among males, 38% among females) and cerebrovascular disease (34% among males, 37% among females) are accountable for the largest proportion of CVDs. In 2008, heart attack and stroke were responsible for 7.3 million deaths and 6.2 million deaths subsequently. Obstructive coronary and cerebrovascular disease are caused in most instances by atherosclerosis. It is a life-time illness that over time can eventually lead to obstructive disease. Once atherosclerotic lesions become clinically significant, serious acute complications such as ischemic heart disease, MI and stroke may occur. This chapter concerns the complex pathological process of atherosclerosis, possible consequences of atherosclerosis and the most recent treatment for atherosclerosis in order to prevent CVD’s. | Since the 20th century, cardiovascular diseases (CVD’s) have grown to be the leading cause of death and disability in the world, illustrated by 17.3 million deaths per year in 2008. Out of all cardiovascular diseases, coronary heart disease (46% among males, 38% among females) and cerebrovascular disease (34% among males, 37% among females) are accountable for the largest proportion of CVDs. In 2008, heart attack and stroke were responsible for 7.3 million deaths and 6.2 million deaths subsequently. Obstructive coronary and cerebrovascular disease are caused in most instances by atherosclerosis. It is a life-time illness that over time can eventually lead to obstructive disease. Once atherosclerotic lesions become clinically significant, serious acute complications such as ischemic heart disease, MI and stroke may occur. This chapter concerns the complex pathological process of atherosclerosis, possible consequences of atherosclerosis and the most recent treatment for atherosclerosis in order to prevent CVD’s. | ||
{{multiple image | {{multiple image | ||
| | | align = center | ||
| | | direction = horizontal | ||
|width = 240 | | width = 240 | ||
|image1 = | | image1 = Figure_1_-_World_map_CVD_mortality_rates_in_males.png | ||
|caption1 = Figure 1. World map CVD mortality rates in males | | caption1 = Figure 1. World map CVD mortality rates in males | ||
|image2 = | | image2 = Figure_2_-_World_map_CVD_mortality_rates_in_females.png | ||
|caption2 = Figure 2. World map CVD mortality rates in females | | caption2 = Figure 2. World map CVD mortality rates in females | ||
|image3 = Figure 3 - Distribution of CVD death among males in 2008.png | | image3 = Figure 3 - Distribution of CVD death among males in 2008.png | ||
|caption3 = Figure 3. Distribution of CVD death among males in 2008 | | caption3 = Figure 3. Distribution of CVD death among males in 2008 | ||
|image4 = Figure 4 - Distribution of CVD death among females in 2008.png | | image4 = Figure 4 - Distribution of CVD death among females in 2008.png | ||
|caption4 = Figure 4. Distribution of CVD death among females in 2008 | | caption4 = Figure 4. Distribution of CVD death among females in 2008 | ||
}} | }} | ||
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