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Cardiac Arrhythmias: Difference between revisions
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→Phase 3: Final Rapid Repolarization
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===Phase 3: Final Rapid Repolarization=== | ===Phase 3: Final Rapid Repolarization=== | ||
Final repolarization is mainly caused by inactivation of Ca<sup>2+</sup> channels, reducing the influx of positive ions. Furthermore repolarizing K<sup>+</sup> currents (delayed rectifier current I<sub>Ks</sub> and I<sub>Kr</sub> and inwardly rectifying current I<sub>K1</sub> and I<sub>K,Ach</sub>) are activated which increase efflux of positive ions. This | Final repolarization is mainly caused by inactivation of Ca<sup>2+</sup> channels, reducing the influx of positive ions. Furthermore repolarizing K<sup>+</sup> currents (delayed rectifier current I<sub>Ks</sub> and I<sub>Kr</sub> and inwardly rectifying current I<sub>K1</sub> and I<sub>K,Ach</sub>) are activated which increase efflux of positive K<sup>+</sup> ions. This results in an repolarization to the resting membrane potential. | ||
===Phase 4: Resting membrane potential=== | ===Phase 4: Resting membrane potential=== | ||