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Cardiac Arrhythmias: Difference between revisions
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→Phase 1: Early Rapid Repolarization
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===Phase 1: Early Rapid Repolarization=== | ===Phase 1: Early Rapid Repolarization=== | ||
Immediately following rapid depolarization, the inactivation of I<sub>Na</sub> and subsequent activation of the outward K<sup>+</sup> current I<sub>TO</sub> and the Na<sup>+</sup>/Ca<sup>2+</sup> exchanger produce a early rapid repolarization. Due to the absence of I<sub>Na</sub> in the upstroke of sinus node and AV node cells and the subsequent slower depolarization, this rapid repolarisation is not visible in their action potentials. | Immediately following rapid depolarization, the inactivation of the Na<sup>+</sup> channel (I<sub>Na</sub>) and subsequent activation of the outward K<sup>+</sup> current (I<sub>TO</sub>) and the Na<sup>+</sup>/Ca<sup>2+</sup> exchanger produce a early rapid repolarization. Due to the absence of I<sub>Na</sub> in the upstroke of sinus node and AV node cells and the subsequent slower depolarization, this rapid repolarisation is not visible in their action potentials. | ||
===Phase 2: Plateau=== | ===Phase 2: Plateau=== | ||