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ICD Primary prevention trials: Difference between revisions
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! Study | |||
! Inclusion Criteria | |||
! Number Randomized | |||
! Control Group | |||
! Primary Point | |||
! Main Finding | |||
|- | |||
| MADIT I<sup>35</sup> | |||
| Prior MI, EF ≤35%, NSVT, inducible and nonsuppressible VT on EPS, NYHA class I–III | |||
| 196 | |||
| Conventional therapy | |||
| All-cause mortality | |||
| 54% RRR in all-cause | |||
mortality with ICD (''P''=0.009); absolute RR 23% | |||
|- | |||
| CABG-PATCH<sup>36</sup> | |||
| EF <35%, abnormal SAECG, elective CABG | |||
| 900 | |||
| Conventional therapy | |||
| All-cause mortality | |||
| No difference in all-cause mortality | |||
|- | |||
| MUSTT<sup>37</sup> | |||
| Prior MI, EF ≤40%, NSVT, inducible VT on EPS | |||
| 704 | |||
| EP-guided antiarrhythmic therapy or conventional therapy | |||
| Cardiac arrest or death due to arrhythmia | |||
| 60% RRR in all-cause mortality with ICD (''P''=0.001); absolute RR 31% | |||
|} | |||