Atherosclerosis: Difference between revisions

Atherosclerosis (view source)

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→‎Complications of atherosclerosis

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 There are several major complications, such as calcification, rupture, hemorrhage, embolization and weakening of the vessel wall that can lead to serious clinical consequences by acute restriction of blood flow or alterations in arterial wall integrity. Clinically, atherosclerosis can lead to major cardiovascular disease:
-* 1.Atherosclerotic plaque can be calcified, which leads to higher rigidity of the vessel wall and therefore favor its fragility.
+# Atherosclerotic plaque can be calcified, which leads to higher rigidity of the vessel wall and therefore favor its fragility.
-* 2.When the plaque ruptures, it will release its pro-coagulants to blood and that will lead to the formation of thrombus at the rupture site. This thrombus may cause a complete occlusion of the vessel and result in acute infarction of the involved organ. Or, the thrombus is  incorporated into another plaque and continues the process of atherogenesis.
+# When the plaque ruptures, it will release its pro-coagulants to blood and that will lead to the formation of thrombus at the rupture site. This thrombus may cause a complete occlusion of the vessel and result in acute infarction of the involved organ. Or, the thrombus is  incorporated into another plaque and continues the process of atherogenesis.
-* 3.Fibrous cap or micro vessels, which are formed within the plaque can rupture and cause hemorrhage within the plaque. This hemorrhage results in intramural hematoma and may contribute to the occlusion of the vessel.
+# Fibrous cap or micro vessels, which are formed within the plaque can rupture and cause hemorrhage within the plaque. This hemorrhage results in intramural hematoma and may contribute to the occlusion of the vessel.
-* 4.Embolization is the transfer of the fragments of disrupted atheroma to distal vascular sites, which results into occlusion of those sites.
+# Embolization is the transfer of the fragments of disrupted atheroma to distal vascular sites, which results into occlusion of those sites.
-* 5.After a chronic period, fibrous plaque can increase the pressure of the medial layer, which results into atrophy and loss of elastic tissue, forming dilatation and weakness of the artery, causing aneurysm.
+# After a chronic period, fibrous plaque can increase the pressure of the medial layer, which results into atrophy and loss of elastic tissue, forming dilatation and weakness of the artery, causing aneurysm.