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Aortic valve stenosis has a severe prognosis when any symptoms are present, with survival rates of only 15–50% at 5 years. Strongest predictors of poor outcome in the elderly population are high New York Heart Association (NYHA) class (III/IV), associated mitral regurgitation and left ventricular dysfunction. Survival is only 30% at 3 years with the combination of these three factors. | Aortic valve stenosis has a severe prognosis when any symptoms are present, with survival rates of only 15–50% at 5 years. Strongest predictors of poor outcome in the elderly population are high New York Heart Association (NYHA) class (III/IV), associated mitral regurgitation and left ventricular dysfunction. Survival is only 30% at 3 years with the combination of these three factors. | ||
= Bicuspid Aortic valve = | |||
[[Image:Heart bicuspid aortic valve.svg|thumb|right|400px|Heart bicuspid aortic valve anatomy by Patrick J. Lynch, medical illustrator, 2006]] | [[Image:Heart bicuspid aortic valve.svg|thumb|right|400px|Heart bicuspid aortic valve anatomy by Patrick J. Lynch, medical illustrator, 2006]] | ||
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Life expectancy in adult patients with bicuspid aortic valve disease is not shortened when compared to the general population. 10-year survival in asymptomatic adults with bicuspid aortic valve disease with a spectrum of valve function, was 96%.<cite>Tzemos</cite> In asymptomatic adults with bicuspid aortic valve disease without significant valve dysfunction the 20-year survival was 90%.<cite>Michelena</cite> | Life expectancy in adult patients with bicuspid aortic valve disease is not shortened when compared to the general population. 10-year survival in asymptomatic adults with bicuspid aortic valve disease with a spectrum of valve function, was 96%.<cite>Tzemos</cite> In asymptomatic adults with bicuspid aortic valve disease without significant valve dysfunction the 20-year survival was 90%.<cite>Michelena</cite> | ||
= Aortic Regurgitation = | = Aortic Regurgitation = | ||
A variety of aetiologies can cause aortic regurgitation by preventing proper coaptation of the aortic valve leaflets with a subsequent diastolic reflux of blood from the aorta into the left ventricle. Etiology of aortic regurgitation can be primary valvular, or it can be primarily caused by aortic root or disease. | A variety of aetiologies can cause aortic regurgitation by preventing proper coaptation of the aortic valve leaflets with a subsequent diastolic reflux of blood from the aorta into the left ventricle. Etiology of aortic regurgitation can be primary valvular, or it can be primarily caused by aortic root or disease. |